Bifurcation analysis of hepatitis B virus with non-cytolytic cure process on infected liver and blood cells

Bifurcation analysis of hepatitis B virus with non-cytolytic cure process on infected liver and blood cells

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Abstract The phenomenon of bifurcation itsmajorlook.com in disease transmission models has been observed in a number of epidemiological models.The consequence of bifurcation is that the classical requirement of the reproduction number being less than unity becomes only a necessary, but not sufficient, for disease elimination.This paper addresses the problem of finding the causes of bifurcation in standard deterministic models for the spread of HBV diseases with non-Cytolytic cure processes on infected liver and blood cells.The model contains logistic growth of healthy liver and blood cells and non -Cytolytic cure processes of infected cells.

I have got that the model exhibits back metabo 15-gauge finish nailer cordless ward and forward bifurcations with some conditions.The existence of a backward bifurcation is an interesting artifact since this means that the disease cannot be eradicated by simply reducing the value of the basic reproduction number $${R}_{0}$$ R 0 below 1.This can have important implications on drug therapy protocols, since it sheds light on possible control mechanisms for disease eradication.